A test and a comparison of the effects of the prevailing physical education programs in the Terre Haute, Indiana high schools

Not available.Robert Paul SnyderNot ListedNot ListedMaster of ArtsDepartment Not ListedCunningham Memorial Library, Terre Haute, Indiana State University.isua-thesis-1947-snyderMastersTitle from document title page. Document formatted into pages: contains 135p. : ill. Includes appendix and bibliography

An Assessment of Alternative State Space Models for Count Time Series

This paper compares two alternative models for autocorrelated count time series. The first model can be viewed as a 'single source of error' discrete state space model, in which a time-varying parameter is specified as a function of lagged counts, with no additional source of error introduced. The second model is the more conventional 'dual source of error' discrete state space model, in which the time-varying parameter is driven by a random autocorrelated process. Using the nomenclature of the literature, the two representations can be viewed as observation-driven and parameter-driven respectively, with the distinction between the two models mimicking that between analogous models for other non-Gaussian data such as financial returns and trade durations. The paper demonstrates that when adopting a conditional Poisson specification, the two models have vastly different dispersion/correlation properties, with the dual source model having properties that are a much closer match to the empirical properties of observed count series than are those of the single source model. Simulation experiments are used to measure the finite sample performance of maximum likelihood (ML) estimators of the parameters of each model, and ML-based predictors, with ML estimation implemented for the dual source model via a deterministic hidden Markov chain approach. Most notably, the numerical results indicate that despite the very different properties of the two models, predictive accuracy is reasonably robust to misspecification of the state space form.Discrete state-space model; single source of error model; hidden Markov

The Ursinus Weekly, February 18, 1910

Valentine fete • Ursinus College song • Charmidean smoker • Phi Alpha Psi Club entertains • The 1911 Ruby • Alumni • Society notes • Personals • Academy notes • Der Deutsche vereinhttps://digitalcommons.ursinus.edu/weekly/2825/thumbnail.jp

From aid to development partnership

노트 : This publication has been made possible by the generous support of the Korea Foundation and Friends of the Asia Foundation Korea. This is the most frequently used resource during 20140721-20140727

What treatment approach to intrapartum maternal fever has the best fetal outcomes?

A combination of beta-lactam and amino-glycoside antibiotics are the recommended empiric agents for the treatment of acute chorioamnionitis, given that no head-to-head trials exist (strength of recommendation [SOR]: C, based on expert opinion). Intrapartum antibiotic treatment is not superior to postpartum antibiotics for reducing neonatal sepsis and pneumonia (SOR: C, based on patient-oriented, underpowered randomized trials)

Normative analysis: A method for determining a need for and verifying success in accommodative and convergence visual training cases

Normative analysis: A method for determining a need for and verifying success in accommodative and convergence visual training case

Recoiling black holes: prospects for detection and implications of spin alignment

Supermassive black hole (BH) mergers produce powerful gravitational wave (GW) emission. Asymmetry in this emission imparts a recoil kick to the merged BH, which can eject the BH from its host galaxy altogether. Recoiling BHs could be observed as offset active galactic nuclei (AGN). Several candidates have been identified, but systematic searches have been hampered by large uncertainties regarding their observability. By extracting merging BHs and host galaxy properties from the Illustris cosmological simulations, we have developed a comprehensive model for recoiling AGN. Here, for the first time, we model the effects of BH spin alignment and recoil dynamics based on the gas-richness of host galaxies. We predict that if BH spins are not highly aligned, seeing-limited observations could resolve offset AGN, making them promising targets for all-sky surveys. For randomly-oriented spins, less than about 10 spatially-offset AGN may be detectable in HST-COSMOS, and > 10^3 could be found with Pan-STARRS, LSST, Euclid, and WFIRST. Nearly a thousand velocity-offset AGN are predicted within the SDSS footprint; the rarity of large broad-line offsets among SDSS quasars is likely due in part to selection effects but suggests that spin alignment plays a role in suppressing recoils. Nonetheless, in our most physically motivated model where alignment occurs only in gas-rich mergers, hundreds of offset AGN should be found in all-sky surveys. Our findings strongly motivate a dedicated search for recoiling AGN.Comment: 30 pages, 19 figures. Accepted to MNRAS after minor revision

Phosphorylation of Spinophilin Modulates Its Interaction with Actin Filaments

Spinophilin is a protein phosphatase 1 (PP1)- and actin-binding protein that modulates excitatory synaptic transmission and dendritic spine morphology. We report that spinophilin is phosphorylated in vitro by protein kinase A (PKA). Phosphorylation of spinophilin was stimulated by treatment of neostriatal neurons with a dopamine D1 receptor agonist or with forskolin, consistent with spinophilin being a substrate for PKA in intact cells. Using tryptic phosphopeptide mapping, site-directed mutagenesis, and microsequencing analysis, we identified two major sites of phosphorylation, Ser-94 and Ser-177, that are located within the actin-binding domain of spinophilin. Phosphorylation of spinophilin by PKA modulated the association between spinophilin and the actin cytoskeleton. Following subcellular fractionation, unphosphorylated spinophilin was enriched in the postsynaptic density, whereas a pool of phosphorylated spinophilin was found in the cytosol. F-actin co-sedimentation and overlay analysis revealed that phosphorylation of spinophilin reduced the stoichiometry of the spinophilin-actin interaction. In contrast, the ability of spinophilin to bind to PP1 remained unchanged. Taken together, our studies suggest that phosphorylation of spinophilin by PKA modulates the anchoring of the spinophilin-PP1 complex within dendritic spines, thereby likely contributing to the efficacy and plasticity of synaptic transmission